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AssigneesArizona Board of Regents on behalf of Arizona State University, The Board of Trustees of the Leland Stanford Junior University, The U.S. Government represented by the Department of Veteran Affairs
InventorsJunseok Chae, Jennie Appel, Joseph Liao
Estimating the term…
Systems and methods for performing cancer screening assays are disclosed. The disclosed systems and methods use a thin film comprising cross-linked polysiloxane. At least a portion of a biological sample to be assayed is contacted with the thin film, along with a cell culture media. After a subsequent incubation period, the thin film is visualized to detect a wrinkle pattern (or lack thereof). The presence of one or more wrinkles and/or a higher degree of wrinkling in the thin film indicates the presence of cancer cells in the biological sample. The disclosed systems and methods can be incorporated into improved assays and kits for cancer screening.
A method for detecting the presence of one or more cancer cells in a biological sample, the method comprising:
The method of 1, wherein the polysiloxane is cross-linked by heating the polysiloxane.
A method of screening for cancer in a subject, the method comprising:
A kit for performing a cancer screening assay, the kit comprising:
Dependencies are inferred from the claim text.