Medical device position location systems, devices and methods

A medical device locating system for determining a disposition of a sensor coil in a subject, the system comprising:

• an array of three or more quadruplet drive coil sets, each drive coil set including at least four discrete drive coils, the at least four discrete drive coils including a first drive coil, a second drive coil, a third drive coil, and a fourth drive coil, the first drive coil being orthogonal to the second drive coil, and at least one of the third drive coil and the fourth drive coil being non-orthogonal to the first and second drive coils, each of the discrete drive coils being electromagnetic coils and configured to generate respective electromagnetic wave fields;
• at least one moveable sensor coil configured to be disposed in a subject and to provide one or more sensor coil response signals responsive to the respective electromagnetic wave fields;
• a receiving component configured to control drive signals to the array of drive coil sets and to measure sensor coil response signals from the moveable sensor coil,
• wherein controlling the drive signals includes providing at least one drive signal and sequentially or simultaneously energizing one or more of said discrete drive coils,
• wherein the receiving component provides a modified drive signal to maximize or optimize:
• the generated respective electromagnetic wave fields, or
• the one or more sensor coil response signals;
• and
• a processor is configured to determine a sensor coil disposition in the subject relative to said quadruplet drive coil sets from one or more sensor coil response signals.