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US 10,119,915 B2Granted
Detection device for specimens
AssigneeVisEra Technologies Company Limited
InventorsZong-Ru Tu, Chin-Chuan Hsieh, Wei-Ko Wang
Life of this patent
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Abstract
A detection device for specimens includes an image sensor, a light-guiding structure, a carrier, and a light source. The light-guiding structure is disposed on the image sensor, and includes a light-guiding layer and a top layer. The light-guiding layer is disposed on the image sensor. The top layer is disposed on the light-guiding layer. The carrier is disposed on the light-guiding structure. The carrier has a number of wells arranged in an array located over the guiding portions. Each of the wells is configured to receive a specimen.
Claims16
A detection device for specimens, comprising:
- an image sensor;
- a light-guiding structure, disposed on the image sensor, comprising:
- a light-guiding layer disposed on the image sensor;
- and
- a top layer disposed on the light-guiding layer;
- a carrier, disposed on the light-guiding structure, having a plurality of wells arranged in a second array located over the top layer, wherein each of the wells is configured to receive and hold a specimen solely within the well, and
- a light source adjacent to a side surface of the light-guiding layer and configured to emit an excitation beam into the light-guiding layer, wherein a portion of the excitation beam is transmitted from the light source along the light-guiding layer to the plurality of wells and another portion of the excitation beam is transmitted from the light source to the microlenses and is reflected by the microlenses to the plurality of wells,
- wherein the top layer includes a plurality of guiding portions, disposed on the light-guiding layer, arranged in a first array, and the wells located over the guiding portions,
- wherein the excitation beam is transmitted to the specimens via the top layer,
- wherein the carrier comprises a top surface and a bottom surface and the plurality of wells is arranged in contact with the top surface of the carrier and the bottom surface of the carrier is opposite of the top surface, and
- wherein the specimens emit induced beams when the specimens are irradiated by the excitation beam, and the detection device is configured so that the induced beams are transmitted from at least one well then through the bottom surface of the carrier and then to the image sensor via the top layer and the light-guiding layer, in sequence.
8 more elements
A detection device for specimens, comprising:
- an image sensor comprising a plurality of micro lenses arranged in a first array;
- a light-guiding structure, comprising:
- a light-guiding layer disposed on the micro lenses;
- and
- a top layer disposed on the light-guiding layer;
- a carrier, disposed on the light-guiding structure, having a plurality of wells arranged in a second array located over the top layer, wherein each of the wells is configured to receive and hold a specimen solely within the well, and
- a light source adjacent to a side surface of the light-guiding layer and configured to emit an excitation beam into the light-guiding layer, wherein a portion of the excitation beam is transmitted from the light source along the light-guiding layer to the plurality of wells and another portion of the excitation beam is transmitted from the light source to the microlenses and is reflected by the microlenses to the plurality of wells,
- wherein the top layer includes a plurality of guiding portions, disposed on the light-guiding layer, arranged in a first array, and the wells located over the guiding portions,
- wherein the excitation beam is transmitted to the specimens via the top layer,
- wherein the carrier comprises a top surface and a bottom surface and the plurality of wells is arranged in contact with the top surface of the carrier and the bottom surface of the carrier is opposite of the top surface, and
- wherein the specimens emit induced beams when the specimens are irradiated by the excitation beam, and the detection device is configured so that the induced beams are transmitted from at least one well then through the bottom surface of the carrier and then to the image sensor via the top layer and the light-guiding layer, in sequence.
8 more elements
Dependencies are inferred from the claim text.