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AssigneesUniversite Technologie De Compiegne—UTC, Centre National de la Recherche Scientifique (CNRS)
InventorsCécile Legallais, Régis Baudoin, Eric Leclerc, Jean-Matthieu Prot, Patrick Paullier
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The present invention relates to a unit (1) comprising a microsystem (150) and at least one set of interface connections (16) for the microsystem (150); the microsystem (150) comprising a bottom plate (152) bearing the impression of at least one microstructured dynamic cell culture chamber (15), and a top plate (151), characterized in that the at least one microstructured chamber (15) is fluidically connected at inlet and/or at outlet by a set of connections (16) inserted removably into a hole in the upper plate (151). The present invention also relates to a dynamic cell culture system to this effect.
A box (1) comprising a microsystem (150), a multi-well plate (110), and at least one set of interface connectors (16), the microsystem (150) comprising a lower plate (152) bearing the impression of at least one microstructured chamber of dynamic cellular culture (15), and an upper plate (151),
The box as claimed in the preceding claim, wherein said box further comprises at least one well (10), the hole (11) is the hole of the at least one well (10), and the microstructured chamber of dynamic cellular culture (15) is connected to said well (10) via one set of the at least one set of interface connectors (16).
The box as claimed in the preceding claim, wherein the bottom of the well (10) is at an altitude higher than any point of the microstructured chamber of dynamic cellular culture (15).
The box as claimed in the preceding claim, wherein the one set of interface connectors (16) is fixed to the hole (11) at the bottom of the well (10).
The box as claimed in the preceding claim, wherein said box comprises a lower casing (100) covered by a sealed hood (200) held by gripping means (20).
The box as claimed in the preceding claim, wherein the lower casing (100) comprises the microsystem (150) and the multi-well plate (110).
The box as claimed in the preceding claim, wherein the multi-well plate (110) is a disposable plate made of polystyrene.
The box as claimed in the preceding claim, wherein said box comprises a male connector (204) and a female connector (201a) per inlet well (10a) and a male connector (204) and two female connectors (201b-c) per outlet well (10b).
The dynamic cellular culture system as claimed in the preceding claim, wherein the circulation means (320) is a multichannel peristaltic pump.
Dependencies are inferred from the claim text.