Back to results
US 10,118,943 B2Granted
Compounds and methods for inhibiting cell death
AssigneeRamot at Tel-Aviv University Ltd.
InventorsIllana Gozes, Saar Oz, Jacqueline Woang Cheing Tiong
Life of this patent
Estimating the term…
Abstract
This invention provides novel compounds and methods for promoting cell survival and/or plasticity, especially in neuronal cells, by targeting the microtubule End Binding (EB) proteins and other associated proteins (e.g., drebrin). Methods for identifying potential modulators of cell death/plasticity are also described.
Claims12
An isolated peptide consisting of the amino acid sequence of SKIP (SEQ ID NO:
- 6), which is acetylated at the N-terminus and amidated at the C-terminus in an effective amount to inhibit cell death or increase cell plasticity.
Dependencies are inferred from the claim text.