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US 10,118,923 B2Granted
Compositions and methods for inhibiting kinases
AssigneeInhibikase Therapeutics, Inc.
InventorsMilton H. Werner, Terence A. Kelly
Life of this patent
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Abstract
The present invention provides compounds for the prevention or treatment of cancer or a bacterial or viral infection. Additionally, the present invention provides compositions and methods for using these compounds and compositions in the prevention or treatment of cancer or a bacterial or viral infection in a subject.
Claims13
A method of treating a mammal suffering from a bacterial infection or a viral infection, comprising administering to the mammal an effective amount of a compound of Formula (I) or a pharmaceutical composition thereof:
- wherein, independently for each occurrence,
- R1 is hydrogen, lower alkyl, —CH3, —CDH2, —CD2H, or —CD3;
- and
- Cy1 is heterocyclyl or substituted or unsubstituted 5-membered heteroaryl,
- wherein the bacterial infection is caused by Pseudomonas aeruginosa, Chlamydia trachomatis, Escherichia coli, Helicobacter pylori, Salmonella typhimurium, Shigella flexneri, or Mycobacterium tuberculosis;
- and
- the viral infection is caused by a Vaccinia virus, a variola virus, a polyoma virus, a Pox virus, a Herpes virus, cytomegalovirus, a human immunodeficiency virus, JC polyomavirus, BK polyomavirus, Simian virus 40, Monkeypox virus, Ebola virus, Marburg virus, Flavivirus, or West Nile virus.
4 more elements
Dependencies are inferred from the claim text.