Deuterated 1-piperazino-3-phenyl indanes for treatment of schizophrenia
AssigneeH. Lundbeck A/S
InventorsMorten Jorgensen, Peter Hongaard Andersen, Klaus Gjervig Jensen
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Abstract
The present invention relates to deuterated 1-piperazino-3-phenyl-indanes and salts thereof with activity at dopamine receptors D1 and D2 as well as the 5HT2 receptors in the central nervous system, to medicaments comprising such compounds as active ingredients, to the use of such compounds in the treatment of diseases in the central nervous system, and to methods of treatment comprising administration of such compounds.
Claims9
A method of treating schizophrenia, schizophreniform disorder, or schizoaffective disorder in a subject in need thereof comprising administration of an effective amount of the hydrochloride salt of a deuterium enriched compound of formula Y:
- wherein,
- R1-R10 are independently hydrogen or deuterium, wherein at least two of R1-R10 are deuterium.
Dependencies are inferred from the claim text.