Topical anti-pruritic compositions and methods of action of same
AssigneeStiefel Laboratories, Inc.
InventorsKathleen L. Clark, Joanne M. Fraser
Life of this patent
Estimating the term…
Abstract
Topical anti-pruritic compositions and methods of using the same to treat pruritus. These anti-pruritic compositions are capable of temporarily or permanently reducing, inhibiting, treating, ameliorating, and/or preventing pruritic skin conditions, as well as other related skin conditions. In a particular aspect, the present formulations provide a quicker and more effective treatment of pruritus than do certain present pruritus-treating compositions.
Claims8
A method for treating pruritus in a patient comprising administering to a patient suffering from pruritus a first topical composition that is a lotion consisting essentially of pramoxine or a pharmaceutically acceptable salt thereof in an amount from about 0.1 to about 5% by weight,
- at least one occlusive skin conditioning agent in an amount from about 1 to about 10% by weight,
- an organosiloxane in an amount from about 0.5 to about 5% by weight,
- an emulsifier in an amount from about 0.5 to about 10% by weight,
- a gelling agent selected from the group consisting of gum arabic, gum tragacanth, locust beam gum, guar gum, xanthan gum, and carbomer, in an amount of about 0.1 to about 2% by weight,
- an emollient in an amount of about 0.01 to about 5% by weight,
- and an aqueous solvent in an amount from about 60 to about 90% by weight, wherein the administration of said first composition provides a more effective treatment of said pruritus in comparison to treatment of pruritus achieved by administration of a second topical composition comprising about 1% by weight hydrocortisone.
Dependencies are inferred from the claim text.