Back to results
US 10,118,038 B2Granted
Methods of neuromodulation
OwnerDirk De Ridderinventor
Life of this patent
Estimating the term…
Abstract
Methods are provided to treat a neurological disorder in a patient by adjusting connectivity between network nodes in a brain of patient using electrical stimulation. Connectivity between network nodes may be increased by synchronous stimulation at multiple network nodes depending upon the neurological disorder. Also, connectivity may be decreased by asynchronous or randomized stimulation at multiple network nodes depending upon the neurological disorder.
Claims16
A method of treating a neurological disorder in a patient, comprising:
- identifying a neural network in the brain of the patient related to the neurological disorder;
- identifying at least two separate target sites in the neural network for stimulation, wherein the at least two separate target sites include a hub site within the neural network;
- providing one or more stimulation leads with electrodes positioned relative to the at least two separate target sites;
- providing electrical stimulation to the at least two separate target sites to adjust function connectivity between the at least two separate target sites to treat the neurological disorder, wherein the providing electrical stimulation generates anticorrelated activity in the at least two separate target sites by concurrently providing burst stimulation to a first site of the at least two separate target sites and providing noise stimulation to a second site of the at least two separate target sites.
1 more element
A method of treating a neurological disorder in a patient, comprising:
- identifying at least two neural networks in the brain of the patient related to the neurological disorder;
- identifying at least two separate target sites in the at least two neural networks for stimulation, wherein the at least two separate target sites include a hub site within one of the at least two neural networks;
- providing one or more stimulation leads with electrodes positioned relative to the at least two separate target sites;
- providing electrical stimulation to the at least two separate target sites to adjust functional connectivity between the at least two neural networks to treat the neurological disorder, wherein the at least two separate target sites include a hub site within a respective neural network, wherein the providing electrical stimulation generates anticorrelated activity in the at least two separate target sites by concurrently providing burst stimulation to a first site of the at least two separate target sites and providing noise stimulation to a second site of the at least two separate target sites.
1 more element
Dependencies are inferred from the claim text.