Methods, devices and systems for pulmonary delivery of active agents

A system for control of pulmonary delivery of pharmacologically active agent, the system comprising:

• an inhaler device operable for pulmonary delivery of at least one vaporized, pharmacologically active agent to a subject, the device including:
• a repository, configured to hold a substance comprising pharmacologically active agent;
• a power source, operable to deliver power to vaporize the pharmacologically active agent from the substance;
• and
• a controller, configured to control delivery of power to the substance, thereby vaporizing metered amounts of the pharmacologically active agent, said controller pre-programmed with at least one predetermined effect to be induced in the subject by said at least one pharmacologically active agent;
• and
• an interface operable to interact with the subject and obtain monitoring data indicative of at least one effect induced in the subject by a vaporized first metered amount of pharmacologically active agent delivered to the subject from the inhaler device, said interface programmed to interact with the subject as a requirement prior to inhalation of a second metered amount of at least one pharmacologically active agent;
• wherein the controller is configured to control delivery of power to the substance to vaporize said second metered amount of pharmacologically active agent for pulmonary delivery to the subject;
• and
• wherein the controller is configured to automatically control a magnitude of the second metered amount of pharmacologically active agent based at least partially on the monitoring data received from the interface and on said at least one predetermined effect.