Agent for regenerating tympanic membrane or external auditory canal
AssigneeNobelpharma AB
InventorShin-ichi Kanemaru
Life of this patent
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Abstract
Provided is a tympanic membrane or ear canal regeneration agent comprising a combination of a gelatin sponge that carries basic fibroblast growth factor (bFGF) and a covering material. The covering material is used not only to fix the gelatin sponge to the affected portion, but also for the purpose of preventing drying and infections to provide a culturing environment that is favorable for regenerating tissue isolated from the outside. To promote tissue regeneration, the margin of the tympanic membrane or ear canal defect is preferably freshened in advance.
Claims5
A tympanic membrane or ear canal regeneration agent comprising:
- (1) a gelatin sponge that carries a therapeutically effective amount of basic fibroblast growth factor to regenerate a tympanic membrane perforation or ear canal soft tissue defect in a subject having a tympanic membrane perforation or ear canal soft tissue defect and (2) fibrin glue as a covering material, and (3) a material insulating the regenerating portion from the outside.
Dependencies are inferred from the claim text.