Medical adhesives for stopping heavy bleeding and sealing leakages

A method of staunching the loss of blood (haemostatic) or tissue fluids comprising:

• a. providing a formulation comprising
• A) an isocyanate-functional prepolymer obtained from
• A1) an aliphatic isocyanate and
• A2) a polyol component having a number-average molecular weight of greater than or equal to 400 g/mol and an average OH functionality of 2 to 6,
• B) a curing component comprising
• B1) an amino-functional aspartic ester of the general formula (I)
• where
• X is an organic radical obtained by removing the primary amino groups from 1,3-diaminopentane, 1,5-diaminopentane, or 1, 13-diamino-4,7,10-trioxatridecane,
• R1 and R2 are ethyl and
• n is 2
• b. applying the formulation to a cell tissue;
• wherein the cell tissue comprises human or animal tissue;
• and
• c. curing the formulation such that the loss of blood (haemostatic) or tissue fluids is staunched,
• wherein the formulation is applied in an in vivo application or an in vitro application.