Pharmaceutical compositions comprising nebivolol or a nebivolol analogue

A pharmaceutical composition for oral administration comprising an active ingredient and a wetting agent, wherein the pharmaceutical composition is a solid pharmaceutical composition in the form of a tablet, wherein the active ingredient is nebivolol hydrochloride, the wetting agent is polysorbate 80, the pharmaceutical composition comprises, on a weight percentage basis, from about 0.01% to about 0.04% of the wetting agent and from about 0.5% to about 10% of the active ingredient, and the ratio (w/w) of wetting agent to active ingredient is less than 0.025,

• wherein the composition further comprises from about 20% to about 80% of a spray dried mixture of microcrystalline cellulose and lactose and/or lactose monohydrate, from about 1% to about 4% of hydroxypropylmethylcellulose, from about 2% to about 30% of corn starch and/or croscarmellose sodium, from about 0.25% to about 2% of magnesium stearate and from about 0.1% to about 2% of colloidal silicon dioxide, and
• wherein the active ingredient is added to the pharmaceutical composition in the form of unmicronized solid particles having a specific surface area of less than 23×103 cm2/g.