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AssigneeZoetis Services LLC
InventorsPaul Joseph Dominowski, Dennis L. Foss, Guillermo Gallo, John Morgan Hardham, Richard Lee Krebs, Sandra Ann Marie Lightle, Suman Mahan, Sangita Mediratta, Kaori Mohr, Duncan Mwangi, Sharath K. Rai, Sarah A. Salmon, Shaunak Vora, Lauren Wilmes
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The instant invention provides various formulations comprising combinations of immunostimulating oligonucleotides, polycationic carriers, sterols, saponins, quaternary amines, TLR-3 agonists, glycolipids, and MPL-A or analogs thereof in oil emulsions, use thereof in preparations of immunogenic compositions and vaccines, and use thereof in the treatment of animals.
An immunogenic composition comprising an effective amount of a Foot-and-Mouth Disease Virus (FMDV) antigen and an adjuvant formulation comprising an oily phase and an aqueous phase, a polycationic carrier, and a CpG containing immunostimulatory oligonucleotide, wherein the vaccine is a water-in-oil emulsion.
Dependencies are inferred from the claim text.