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US 10,117,862 B2Granted
Remifentanil injection
AssigneeTerumo Kabushiki Kaisha
InventorsAiko Horiuchi, Shigeru Suzuki
Life of this patent
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Abstract
A remifentanil injection solution formulation contains remifentanil and or physiologically acceptable salts thereof, water, and a stabilizer, the remifentanil injection solution formulation contains said water at a rate of 0.007 to 0.025 mL per 1 mg of said remifentanil.
Claims8
A remifentanil injection solution formulation comprising
- water, a stabilizer and remifentanil and/or physiologically acceptable salts thereof,
- wherein said stabilizer is polyethylene glycol or propylene glycol,
- said remifentanil injection solution formulation contains said water at a rate of 0.007 to 0.025 mL per 1 mg of said remifentanil, and
- a content ratio between said water and said stabilizer is set to 2:23 to 2:198 in a volume ratio.
1 more element
A prefilled syringe filled a remifentanil injection solution formulation and subjected to high-pressure steam sterilization,
- wherein said remifentanil injection solution formulation comprises water, a stabilizer and remifentanil and/or physiologically acceptable salts thereof,
- said stabilizer is polyethylene glycol or propylene glycol,
- said remifentanil injection solution formulation contains said water at a rate of 0.007 to 0.025 mL per 1 mg of said remifentanil, and
- a content ratio between said water and said stabilizer is set to 2:23 to 2:198 in a volume ratio.
1 more element
Dependencies are inferred from the claim text.