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US 10,117,859 B2Granted
Dosage suspensions of active pharmaceutical ingredients
AssigneeSouthwest Research Institute
InventorsHong Dixon, Larry A. Cabell, Joseph A. McDonough
Life of this patent
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Abstract
Methods for preparing suspensions of active pharmaceutical ingredients for ensuing drug delivery. The suspension may include a mixture of a relatively low dosage API and a relatively high dosage API or a mixture of an API with a suitable excipient.
Claims11
A method for forming a drug suspension comprising:
- a) providing a first active pharmaceutical ingredient (API-1);
- b) providing a second active pharmaceutical ingredient (API-2);
- c) co-dissolving said API-1 and API-2 in a common solvent;
- d) removing said solvent and recovering a mixture of API-1 and API-2;
- and
- e) forming said drug suspension of said mixture of API-1 and API-2 in a liquid carrier, wherein in said drug suspension, API-1 is present at a concentration of 0.1 mg/mL to 10.0 mg/mL and API-2 is present at a concentration of 20.0 mg/mL to 800 mg/mL.
3 more elements
Dependencies are inferred from the claim text.