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US 10,117,838 B2Granted
Pharmaceutical composition for the prolonged release of trimetazidine
AssigneeLes Laboratoires Servier
InventorsPatrick Genty, Christophe Hermelin, Jean-Manuel Pean
Life of this patent
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Abstract
Composition for the prolonged release of trimetazidine wherein the inner phase comprises trimetazidine and the outer layer comprises a retardant and an anti-agglomerant.
Claims16
A pharmaceutical composition for prolonged release of trimetazidine, comprising:
- an inner phase which comprises trimetazidine, or a pharmaceutically acceptable salt thereof, coated onto a neutral core;
- and
- an outer layer consisting of a retardant, an anti-agglomerant, and a plasticiser,
- wherein the percentage of retardant is from 5.5% to 8% of the total weight of the inner phase;
- and the percentage of anti-agglomerant is from 100% to 200% of the weight of the retardant.
2 more elements
Dependencies are inferred from the claim text.