Emulsified fatty acids
AssigneeBarlean's Organic Oils, LLC
InventorPeter Nguyen
Life of this patent
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Abstract
Provided herein are methods and processes for emulsifying non-polar compounds, such as omega fatty acids. Also provided are compositions that can be prepared according to the methods and processes described herein. The compositions, for example, have a high amount of the non-polar compound, such as a large amount of omega fatty acids. The non-polar compounds are also present in very small droplets within composition. For example, the mean or median particle size of the droplets is less than about 5 μm. Further, the composition includes a low amount of surfactant, such as less than about 10-15% of the surfactant.
Claims25
A process for forming an oil-in-water emulsion, comprising combining under high-shear mixing:
- a) an oil phase comprising:
- i) d-α-tocopheryl polyethylene glycol succinate (“TPGS”) or one or more derivatives thereof, and
- ii) one or more non-polar compounds;
- and
- b) an aqueous phase comprising:
- i) less than about 15% by weight of one or more emulsifiers, and
- ii) the balance water and optionally one or more carriers;
- wherein the emulsion comprises less than 2% by weight TPGS or derivatives thereof and about 20% to about 35% by weight of the one or more non-polar compounds and wherein the oil phase droplets have a median particle size greater than 1 μm but less than or equal to 3 μm.
A method for providing an emulsion, comprising:
- providing a first mixture comprising d-α-tocopheryl polyethylene glycol succinate (“TPGS”) or derivative thereof and a non-polar compound or mixture of non-polar compounds, wherein the TPGS or derivative thereof is present in an amount less than 10% by weight of the first mixture and the non-polar compound or mixture of non-polar compounds are present in amount at least 90% by weight of the first mixture;
- providing a second mixture, wherein the second mixture comprises water and one or more emulsifiers and wherein the one or more emulsifiers comprise less than about 15% of the second mixture;
- combining the first mixture with the second mixture under high-shear to form an emulsion of the non-polar compound or mixture of non-polar compounds,
- wherein the non-polar compounds or mixture thereof are present in the emulsion in droplets having a median particle size greater than 1 μm but less than or equal to about 3 μm, wherein the non-polar compounds or mixture thereof comprise about 20% to about 35% by weight of the emulsion, and wherein the TPGS or derivative thereof does not exceed 2% by weight of the emulsion.
An oil-in-water emulsion, comprising water and:
- a) an emulsifier;
- b) d-α-tocopheryl polyethylene glycol succinate (“TPGS”) or a derivative thereof;
- and
- c) about 20% to about 35% by weight of one or more lipids;
- wherein the emulsifier is present in an amount less than 10% by weight of the emulsion, wherein the TPGS is present in an amount less than 2% by weight of the emulsion, and wherein the lipids are present in the emulsion as droplets having a median particle size of greater than 1 μm but less than or equal to about 3 μm.
Dependencies are inferred from the claim text.