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US 10,117,809 B2Granted
Compositions for endodontic procedures
AssigneeDENTSPLY SIRONA Inc.
InventorsTodd Berger, Kevin Wilkinson, Adam Baratz, Dan Ammon
Life of this patent
Estimating the term…
Abstract
An adhesion promoter for endodontic sealant compositions for filling and sealing a root canal.
Claims33
An endodontic composite sealant composition for filling and sealing a root canal comprising an adhesion promoter, wherein the adhesion promoter is characterized by the following formula (I):
- R1—R2—W—Z—R3—R4 (I)
- wherein
- wherein
- R1 and R4 are independently Hydrogen, NH2, OH, COOH, SH, an epoxide, a succunic anhydride, a succinimide group, a phosphate, a sulfate, a sulfonate, a betaine, a carboxylic acid, an amino acid, a diacids, a bisphosphate, or a phosphatidylcholine group;
- R2 and R3 are independently a C1-10 alkyl group, NH2, OH, COOH, SH, an epoxide, a succunic anhydride, a succinimide group, a phosphate, a sulfate, a sulfonate, a betaine, a carboxylic acid, an amino acid, a diacids, a bisphosphate, or a phosphatidylcholine group;
- R5, R6, R7, R8, R9, R10, R11, and R12 are independently Hydrogen, a C1-10 alkyl group, or a C1-10—R13 group such that R13 is independently NH2, OH, COOH, SH, an epoxide, a succunic anhydride, a succinimide group, a phosphate, a sulfate, a sulfonate, a betaine, a carboxylic acid, an amino acid, a diacids, a bisphosphate, or a phosphatidylcholine group, whereas multiple groups of R5, R6, R7, R8, R9, R10, R11, R12, and R13 may be identical or different;
- and
- x is an integer from 1 to 1000, multiple groups of x may be identical or different;
- y is an integer from 1 to 1000, multiple groups of y may be identical or different;
- and
- m is an integer from 1 to 1000, multiple groups of m may be identical or different.
8 more elements
An endodontic composite sealant composition for filling and sealing a root canal comprising an adhesion promoter, wherein the adhesion promoter includes a first component and a second component,
- a) the first component is characterized by the following formula (IIa):
- R1—R2—W—Z—R3—R4 (IIa);
- wherein
- R1 and R4 are independently NH2, OH, COOH, or SH;
- R2 and R3 are independently a C1-10 alkyl group;
- R5, R6, R7, R8, R9, R10, R11 and R12 are independently Hydrogen, a C1-10 alkyl group, or a C1-10—R13 group such that R13 is independently a phosphate, a sulfate, a sulfonate, a betaine, a carboxylic acid, an amino acid, a diacids, a bisphosphate, or a phosphatidylcholine group, whereas multiple groups of R5, R6, R7, R8, R9, R10, R11, R12, and R13 may be identical or different;
- x is an integer from 1 to 1000, multiple groups of x may be identical or different;
- y is an integer from 1 to 1000, multiple groups of y may be identical or different;
- and
- m is an integer from 1 to 10, multiple groups of m may be identical or different;
- and
- b) the second component is characterized by the following formula (IIb):
- R13—R14—W—Z—R15—R16 (IIb);
- wherein
- R13 and R16 are independently an epoxide, a succunic anhydride, or a succinimide group;
- R14 and R15 are independently a C1-10 alkyl group;
- R16, R17, R18, R19, R20, R21, R22, and R23 are independently Hydrogen, a C1-10 alkyl group, or a C1-10—R24 group such that R24 is independently a phosphate, a sulfate, a sulfonate, a betaine, a carboxylic acid, an amino acid, a diacids, a bisphosphate, or a phosphatidylcholine group, whereas multiple groups of R16, R17, R18, R19, R20, R21, R22, R23, and R24 may be identical or different;
- q is an integer from 1 to 1000, multiple groups of q may be identical or different;
- r is an integer from 1 to 1000, multiple groups of r may be identical or different;
- and
- s is an integer from 1 to 10, multiple groups of s may be identical or different.
18 more elements
An endodontic composite sealant composition for filling and sealing a root canal comprising an adhesion promoter, wherein the adhesion promoter includes a first component and a second component,
- a) the first component is characterized by the following formula (IIIa):
- R1—R2—W—Z—R3—R4 (IIIa);
- wherein
- R1 and R4 are independently Hydrogen, a phosphate, a sulfate, a sulfonate, a betaine, a carboxylic acid, an amino acid, a diacids, a bisphosphate, or a phosphatidylcholine group, provided at least one of R1 and R4 is not Hydrogen;
- R2 and R3 are independently a substituted or unsubstituted C1-10 alkyl group;
- R5, R6, R7, R8, R9, R10, R11 and R12 are independently Hydrogen, a C1-10 alkyl group, or a C1-10—R13 group such that R13 is independently NH2, OH, COOH, SH, whereas multiple groups of R7, R8, R9, R10, R11, R12, and R13 may be identical or different;
- x is an integer from 1 to 1000, multiple groups of x may be identical or different;
- y is an integer from 1 to 1000, multiple groups of y may be identical or different;
- and
- m is an integer from 1 to 10, multiple groups of m may be identical or different;
- and
- b) the second component is characterized by the following formula (IIIb):
- R13—R14—W—Z—R15—R16 (IIIb);
- wherein
- R13 and R16 are independently Hydrogen, a phosphate, a sulfate, a sulfonate, a betaine, a carboxylic acid, an amino acid, a diacids, a bisphosphate, or a phosphatidylcholine group, provided at least one of R1 and R4 is not Hydrogen;
- R14 and R15 are independently a substituted or unsubstituted C1-10 alkyl group;
- R16, R17, R18, R19, R20, R21, R22, and R23 are independently Hydrogen, a C1-10 alkyl group, or a C1-10—R24 group such that R24 is independently an epoxide, a succunic anhydride, or a succinimide group, whereas multiple groups of R16, R17, R18, R19, R20, R21, R22, R23, and R24 may be identical or different;
- q is an integer from 1 to 1000, multiple groups of q may be identical or different;
- r is an integer from 1 to 1000, multiple groups of r may be identical or different;
- and
- s is an integer from 1 to 10, multiple groups of s may be identical or different.
18 more elements
An endodontic composite sealant composition for filling and sealing a root canal comprising an adhesion promoter, wherein adhesion promoter is characterized by the following formula (IV):
- R1—W—Z—R2 (IV)
- wherein
- R1 and R2 are independently a substituted or unsubstituted C1-11alkyl group;
- wherein
- R3, R4, R5, R6, R7, R8, R9, and R10 are independently Hydrogen, a C1-10 alkyl group, or a C1-10—R11 group such that R11 is independently NH2, OH, COOH, SH, an epoxide, a succunic anhydride, a succinimide group, a phosphate, a sulfate, a sulfonate, a betaine, a carboxylic acid, an amino acid, a diacids, a bisphosphate, or a phosphatidylcholine group;
- whereas multiple groups of R3, R4, R5, R6, R7, R8, R9, R10, and R11 may be identical or different;
- provided that at least one of R3, R4 R5, R6, R7, and R8 includes the C1-10—R11 group;
- x is an integer from 1 to 1000, multiple groups of x may be identical or different;
- y is an integer from 1 to 1000, multiple groups of y may be identical or different;
- and
- m is an integer from 1 to 10, multiple groups of m may be identical or different.
8 more elements
An endodontic composite sealant composition for filling and sealing a root canal comprising an adhesion promoter, wherein the adhesion promoter includes a first component and a second component,
- a) the first component is characterized by the following formula (IVa):
- R1—W—Z—R2 (IVa)
- wherein
- R1 and R2 are independently a substituted or unsubstituted C1-11 alkyl group;
- wherein
- R3, R4, R5, R6, R7, R8, R9, and R10 are independently Hydrogen, a C1-10 alkyl group, or a C1-10—R11 group such that R11 is independently NH2, OH, COOH, or SH;
- whereas multiple groups of R3, R4, R5, R6, R7, R8, R9, R10, and R11 may be identical or different;
- provided that at least one of R3, R4 R5, R6, R7, and R8 includes the C1-10—R11 group;
- x is an integer from 1 to 1000, multiple groups of x may be identical or different;
- y is an integer from 1 to 1000, multiple groups of y may be identical or different;
- and
- m is an integer from 1 to 10, multiple groups of m may be identical or different;
- and
- b) the second component is characterized by the following formula (IVb):
- R12—W—Z—R13 (IVb)
- wherein
- R12 and R13 are independently a substituted or unsubstituted C1-11 alkyl group;
- wherein
- R14, R15, R16, R17, R18, R19, R20, and R21 are independently Hydrogen, a C1-10 alkyl group, or a C1-10—R22 group such that R22 is independently an epoxide, a succunic anhydride, or a succinimide group;
- whereas multiple groups of R14, R15, R16, R17, R18, R19, R20, R21, and R22 may be identical or different;
- provided that at least one of R14, R15, R16, R17, R18, and R19 includes the C1-10—R11 group;
- q is an integer from 1 to 1000, multiple groups of x may be identical or different;
- r is an integer from 1 to 1000, multiple groups of y may be identical or different;
- and
- s is an integer from 1 to 10, multiple groups of m may be identical or different.
22 more elements
Dependencies are inferred from the claim text.