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US 10,117,774 B2Granted
Apparatus and methods for delivering therapeutic agents
AssigneeUniversity of Southern California
InventorsMark S. Humayun, Sean Caffey
Life of this patent
Estimating the term…
Abstract
In various embodiments, a drug-delivery device includes one or more reservoirs that may each contain a therapeutic agent for delivery to a patient.
Claims20
A drug-delivery device, comprising:
- a first reservoir for containing a first liquid that comprises or consists essentially of a first therapeutic agent;
- a second reservoir for containing a second liquid that comprises or consists essentially of a second therapeutic agent different from the first therapeutic agent;
- and
- a cannula having first, second and third portions, the second and third portions branching off from the first portion to communicate fluidically with the first and second reservoirs, respectively;
- a first fluid-flow isolation structure located in the second portion;
- a second fluid-flow isolation structure located in the third portion;
- memory for storing a drug-delivery regimen;
- a microprocessor for controlling a delivery of the first and second liquids to a patient through the cannula based on an execution of the stored drug-delivery regimen;
- and
- a sensor for detecting a measured eye pressure for the patient;
- wherein the first and second fluid-flow isolation structures prevent fluidic communication between the first and second reservoirs and isolate the first and second reservoirs from an external environment.
8 more elements
A drug-delivery device, comprising:
- a first reservoir for containing a first liquid that comprises or consists essentially of a first therapeutic agent;
- a second reservoir for containing a second liquid that comprises or consists essentially of a second therapeutic agent different from the first therapeutic agent;
- a cannula having first, second and third portions, the second and third portions branching off from the first portion to communicate fluidically with the first and second reservoirs, respectively;
- a first fluid-flow isolation structure located in the second portion;
- a second fluid-flow isolation structure located in the third portion;
- an electrolysis chamber including a gas-impermeable flexible membrane configured to expand and contract with increases and decreases in pressure in the electrolysis chamber, the flexible membrane also constituting a portion of at least one of the first or second reservoir;
- at least two electrodes in the electrolysis chamber, the electrodes being responsive to the microprocessor to produce gas in the electrolysis chamber to expand the membrane and thereby force liquid from at least one of the first or second reservoir through the cannula;
- memory for storing a drug-delivery regimen;
- and
- a microprocessor for controlling a delivery of the first and second liquids to a patient through the cannula based on an execution of the stored drug-delivery regimen
- wherein the first and second fluid-flow isolation structures prevent fluidic communication between the first and second reservoirs and isolate the first and second reservoirs from an external environment.
8 more elements
Dependencies are inferred from the claim text.