Compositions and methods for preserving donated blood
AssigneeRythRx Therapeutics, LLC
InventorNarayanan Surendran
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Abstract
Blood and platelet storage and rejuvenating compositions that include triciribine, triciribine metabolites, triciribine analogs, and mixtures of the same are disclosed. Such compositions can be useful in methods for treating (e.g., storing and rejuvenating) red blood cells and platelets.
Claims19
A method for preserving donated blood for subsequent transfusion into a patient, comprising
- contacting donated blood with triciribine.
A method for preserving donated platelets for subsequent transfusion into a patient, comprising
- contacting donated platelets triciribine.
A method of preserving donated blood for subsequent transfusion into a patient, comprising contacting donated red blood cells with triciribine so that formation of microparticles is reduced by at least 40% after 12 days compared to untreated red blood cells.
Dependencies are inferred from the claim text.