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US 10,082,495 B2Granted
Methods for the detection of oxidative adulterants in urine sample
AssigneeVision Diagnostics, Inc.
InventorJerry W. Denney
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AssigneeVision Diagnostics, Inc.
InventorJerry W. Denney
Estimating the term…
The problem of confirming the presence of an adulterant in a urine sample is solved by the use of a reagent capable of reacting with uric acid and non-urate markers in a urine sample. In one embodiment, a phosphotungtate reagent is used to react with the urine sample to create a blue coloration in the presence of uric acid or uric acid equivalents. A reduction or elimination of the blue coloration, resulting in a reduction in the light absorbance, of the urine sample can be used as an indicator of the historical presence of an adulterant. An Oxidant History test can also be generated using the phosphostungtate reagent, wherein the light absorbance resulting from the blue coloration is measured over time, with a measured reduction in the absorbance being an indication that an adulterant is or has been present in the urine sample and is oxidizing the uric acid and non-urate markers over time.
An assay method for measuring the presence of an oxidative-adulterant in urine, the method comprising:
An assay method that determines a historical presence of an oxidative-adulterant in a urine sample, the method comprising:
A method for obtaining an Oxidant History for a urine sample, the method comprising:
Dependencies are inferred from the claim text.