One-way actuation release mechanism for a system for applying medicament

A system for dispensing medicament, which comprises:

• a vial holding a volume of medicament;
• an elastic, deformable body portion in fluid communication with said vial and containing a dosage cavity for collecting a predetermined volume of medicament from said vial, said deformable body portion having an integral elastomeric spring portion for providing spring action;
• a nozzle portion connected to said deformable body portion for allowing discharge of said medicament collected in said dosage cavity;
• a housing retaining said deformable body portion and said nozzle portion, said housing having an anterior wall with an aperture for receiving said nozzle portion;
• and
• a one-way release-actuation system having a trigger and a release mechanism, said release-actuation system actuating, by a single actuating motion of said trigger, said dispensing system to sequentially fill said dosage cavity with medicament from said vial and subsequently discharge said medicament from said dosage cavity, wherein said release mechanism engages and deforms at least said elastomeric spring portion of said deformable body portion in concert with a first phase of said actuating motion of said trigger, said deformation of said deformable body portion causing flow of medicament from said vial to said dosage cavity to fill said dosage cavity, and wherein said release mechanism disengages itself from said deformable body portion upon continuation of said actuating motion of said trigger into a second phase, said deformable body portion returning to said ambient position by action of said elastomeric spring portion upon disengagement from said release mechanism to pressurize medicament in said dosage cavity and discharge said medicament through said nozzle portion.

A one-way actuation release mechanism for actuating a medicament dispenser having an elastic, deformable body portion, which comprises:

• a trigger;
• and
• a release unit operationally coupled to said trigger and adapted to releasably engage said deformable body portion, said release unit being adapted to deform said deformable body portion from an ambient position towards a first non-ambient position in a first phase of actuation to ready medicament for dispensation, and said release unit being adapted to disengage from said deformable body portion when said body portion has reached said first non-ambient position upon continuation of said actuation into a second phase;
• wherein said one-way actuation release mechanism facilitates said deformable body portion to return to said ambient position upon disengagement from said release unit to discharge said medicament, and wherein said one-way actuation release mechanism facilitates substantially constant spring force of said deformable body portion over an extended period of time by preventing locking of said deformable body portion in any non-ambient position.

A method of dispensing medicament from a dispensing system having one-way actuation release mechanism, an elastic, deformable body portion and a dosage cavity therein, said one-way actuation release mechanism having a trigger and a release unit operationally coupled to said trigger and releasably engaging said deformable body portion, which method comprises:

• deforming said deformable body portion from an ambient position towards a first non-ambient position by actuating said trigger through a first phase of an actuation motion to move a first component of said release unit releasably engaged to said deformable body portion, said deformation causing flow of medicament into said cavity to fill said cavity;
• disengaging said first component of said release unit from said deformable body portion when said deformable body portion has reached said first non-ambient position upon continuation of said actuation motion into a second phase;
• and
• biasing said deformable body portion back toward said ambient position upon disengagement from said release unit to pressurize medicament in said cavity and discharge said medicament;
• wherein said method facilitates maintenance of substantially constant spring force of said deformable body portion over an extended period of time by preventing locking of said deformable body portion in any non-ambient position.

A nasal instill dispenser comprising:

• a nasal dispenser including a vial, a dispenser body, a storage chamber containing a fluid, a channel, and a nozzle in fluid communication with the channel, wherein the nozzle includes a tip that is placeable inside a nostril of a nose for delivering fluid to the nose;
• a housing for retaining the nasal dispenser;
• a pump mechanism that channels the fluid to the nozzle via the channel, wherein the nozzle, the pump mechanism and the storage chamber are arranged along a longitudinal axis;
• and
• an actuation mechanism located laterally to the side of the longitudinal axis, and is movable between a first position toward a second position and then back toward the first position, wherein said movement actuates the pump mechanism (1) to discharge the fluid in the direction of the longitudinal axis and into the nose, and (2) to load the pump mechanism with fluid from the storage chamber.