Compositions capable of reducing elevated blood urea concentration
AssigneeBiotemp B.V.
InventorsRobbert Benner, Nisar Ahmed Khan
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Abstract
The invention includes a method of reducing urea concentration in a subject's serum. Such a method comprises administering to the subject (e.g., a mammal such as a human) a composition comprising an oligopeptide (or oligopeptides) having activity in reducing urea concentration in the subject's serum as determined by a mouse renal reperfusion test, wherein the oligopeptide comprises the sequence AQG or MTRV (SEQ ID NO:1), AQGV (SEQ ID NO:2) or LAGV (SEQ ID NO:4).
Claims4
An isolated oligopeptide consisting of the amino acid sequence of SEQ ID NO:
- 2 or a pharmaceutically acceptable salt thereof.
A pharmaceutical composition comprising a peptide consisting of the amino acid sequence of SEQ ID NO:
- 2 or a pharmaceutically acceptable salt thereof.
An isolated oligopeptide consisting of the amino acid sequence of SEQ ID NO:
- 2.
Dependencies are inferred from the claim text.