Phosphatidyl quaternary ammonium compounds
OwnerBarry D. Searsinventor
Life of this patent
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Abstract
Novel synthetic phosphatidyl ammonium hydroxide compounds are prepared which have a hydrophobic/hydrophilic balance different from the natural phosphatidylcholine, which alterations are carried out by changes in the quaternary ammonium polar group to provide different surfactant properties.
Claims10
A synthetic phosphatidyl quaternary ammonium compound represented by the formula:
- ##STR4## wherein R is a C.sub.14 to C.sub.20 hydrocarbon radical;
- a, b and c represent whole integers of from 0 to .Badd.[3].Baddend. 2 and a, b and c in total are equal to at least one ;
- d represents a whole [integers] integer of [from 1 to 5, except that in combination a, b and c cannot be zero and d cannot be two] 2 ;
- and R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are methylene radicals.
[6. The compound of claim 1 wherein R.sub.4 is a tetramethylene radical and a, b and c are zero.]
[7. The compound of claim 1 wherein R.sub.4 is a trimethylene radical and a, b and c are
- one, and R.sub.1, R.sub.2 and R.sub.3 are a methylene radical.]
[8.
- The compound of claim 6 wherein R is a fatty radical.] 9. The compound of claim 1 wherein ##STR5## is a myristoyl, palmitoyl, oleoyl, linoleoyl, stearoyl, egg yolk or
- soybean radical. 10. The compound of claim 1 selected from the group consisting of:
- [dioleoyl phosphatidyl-(methylethylene-N-triethyl)ammonium;]
- dipalmitoyl phosphatidyl-(ethylene-N-dimethylethyl)ammonium;
- distearoyl phosphatidyl-(ethylene-N-dimethylethyl)ammonium;
- and oleoyl-palmitoyl phosphatidyl-(ethylene-N-dimethylethyl)ammonium[;
- dimyristoyl phosphatidyl-(tetramethylene-N-dipropylmethyl)ammonium;
- dipalmitoyl phosphatidyl-(trimethylene-N-trimethyl)ammonium;
- egg phosphatidyl-(trimethylene-N-trimethyl)ammonium;
- soybean phosphatidyl-(trimethylene-N-trimethyl)amonium;
- and
- dipalmitoyl phosphatidyl-(tetramethylene-N-trimethylene)ammonium].
[11. The compound of claim 6 wherein ##STR6## is a myristoyl, palmitoyl, oleoyl, linoleoyl, stearoyl, egg yolk or
- soybean radical.]
Dependencies are inferred from the claim text.