Compositions and methods for generating a synthetic antibody
AssigneeThe Trustees of the University of Pennsylvania
InventorsDavid B. Weiner, Karuppiah Muthumani, Niranjan Sardesai, Seleeke Flingai
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Abstract
Disclosed herein is a composition including a recombinant nucleic acid sequence that encodes an antibody. Also disclosed herein is a method of generating a synthetic antibody in a subject by administering the composition to the subject. The disclosure also provides a method of preventing and/or treating disease in a subject using said composition and method of generation.
Claims32
A method of generating a synthetic antibody in a subject, the method comprising administering to the subject a composition comprising a recombinant nucleic acid sequence encoding an antibody or an antigen binding fragment thereof, wherein the recombinant nucleic acid sequence is expressed in the subject to generate the synthetic antibody, wherein the nucleic acid sequence comprises a nucleic acid sequence encoding at least one amino acid sequence selected from the group consisting of SEQ ID NOs:
- 41 and 43.
Dependencies are inferred from the claim text.