Substituted 5-flouro-1H-pyrazolopyridines and their use

A method of treating or preventing one or more of coronary heart disease, systolic or diastolic heart failure, angina pectoris, ischaemias, peripheral and cardiac vascular disorders, kidney failure, renal insufficiency, and increased microalbuminurea, comprising administering a therapeutically effective amount of a compound of formula (I)

• in which
• R1 represents hydrogen or (C1-C4)-alkyl,
• where (C1-C4)-alkyl may be substituted by one or two substituents independently of one another selected from the group consisting of fluorine and trifluoromethyl,
• or an N-oxide, salt or salt of an N-oxide thereof to a human or animal in need thereof.