Methods for controlling pests using RNAi
AssigneeDevgen NV
InventorsRomaan Raemaekers, Pascale Feldmann, Geert Plaetinck, Irene Nooren, Els Van Bleu, Frederic Pecqueur, Laurent Kubler, Nicole Damme, Lies Degrave, Isabel Remory, Thierry Bogaert
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Abstract
The present invention relates to methods for controlling pest infestation using double stranded RNA molecules. The invention provides methods for producing transgenic cells expressing the double stranded RNA molecules, as well as compositions and commodity products containing or treated with such molecules.
Claims10
An isolated double stranded ribonucleotide (RNA) molecule, wherein the RNA molecule is a pest control agent targeting a gene encoding beta-coatomer, wherein the RNA molecule comprises complementary strands, wherein one strand of the RNA molecule is produced from the expression of a polynucleotide molecule selected from the group consisting of:
- (a) a polynucleotide molecule comprising the nucleic acid sequence set forth in SEQ ID NO:
- 23, or a fragment of at least 21 nucleotides thereof;
- and
- (b) a polynucleotide molecule comprising a nucleic acid sequence at least 85% identical to SEQ ID NO:
- 23,
- wherein ingestion of said RNA molecule by a pest results in down-regulation of the target gene in the pest.
Dependencies are inferred from the claim text.