US 9,982,019 B2Granted

Glycopeptide compound or pharmaceutical salt thereof and method for preparing same, and pharmaceutical compositions and applications thereof

OwnerDingfeng Zhang, Yuanyuan Ge +7inventors

InventorsDingfeng Zhang, Yuanyuan Ge, Mei Ge, Weicheng Zhou, Wei Wei, Shunli Zhang, Lingao Ruan, Zhenren Liu, Chang Shao

Life of this patent

Estimating the term…

patentgrep

Loading patent…

Abstract

The present invention provides a glycopeptide compound or pharmaceutically acceptable salt thereof as shown in Formula (I) or (II), and a method for preparing same, and pharmaceutical compositions and applications thereof, wherein the definition of R1, R2, R3, R4, R5 is the same as that of the specification. The glycopeptide compound of the present invention has in-vitro antibacterial activity and has important significance for development of new antibacterial agents.

Claims12

Dependent claims

A glycopeptide compound or pharmaceutically acceptable salt thereof of Formula (II),

wherein:
R1 is a mono-substituted benzyl substituted by halogen, methoxy or isopropyl;
a group of NR4R5 is diethylamino, n-butylamino, or morpholino.

Dependencies are inferred from the claim text.

Facts

Application: 14/655,830Filed 26 Dec 2013
Priority: CN 2012 1 058173327 Dec 2012
Published: US 2015/0353607 A110 Dec 2015
Granted: 29 May 2018
Term ends: Not estimatedThe source records don’t support an estimate.

Classification12 codes

C07K 9/006
Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof: the peptide…
A61P 31/04
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics: antibacterial agents
C07K 9/008
The peptide sequence being part of a ring structure: directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin,…
A61K 38/00
Medicinal preparations containing peptides