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US 9,981,901 B2Granted
IRE-1α inhibitors
AssigneeFosun Orinove Pharmatech, Inc.
InventorsJohn B. Patterson, David G. Lonergan, Gary A. Flynn, Qingping Zeng, Peter V. Pallai
Life of this patent
Estimating the term…
Abstract
Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.
Claims2
An IRE-1α inhibitor, wherein the IRE-1α inhibitor is:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.