Probes and methods for the detection of a virus that causes acute enteritis
AssigneeCatholic University Industry Academic Cooperation Foundation
InventorsSoon-young Paik, Yu-jeong Won
Life of this patent
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Abstract
The present invention relates to a composition comprising a probe for detecting six representative causative viruses of acute enteritis (norovirus genogroup I and genogroup II, rotavirus, hepatitis A virus, coxsackievirus, astrovirus, and adenovirus), and a DNA microarray, a kit, and a detection method comprising the composition. The present invention is effective due to high specificity and sensitivity to viruses. In addition, since the causative viruses can simply be detected at low cost compared to conventional detection methods, without expensive diagnosis devices or specialists, the present invention may be effectively used as a method for diagnosing viruses causing acute enteritis.
Claims8
A composition for detecting one or more viruses selected from the group consisting of norovirus types I and II, rotavirus G genotype, hepatitis A virus, coxsackievirus, astrovirus, and adenovirus, comprising one or more probes selected from the group consisting of:
- i) a probe for detecting norovirus types I and II consisting of the polynucleotide set forth in SEQ ID NOs:
- 1 and 2, respectively;
- ii) a probe for detecting rotavirus G genotype consisting of the polynucleotide set forth in SEQ ID NO:
- 3;
- iii) a probe for detecting hepatitis A virus consisting of the polynucleotide set forth in SEQ ID NO:
- 4;
- iv) a probe for detecting coxsackievirus consisting of the polynucleotide set forth in SEQ ID NO:
- 5;
- v) a probe for detecting astrovirus consisting of the polynucleotide set forth in SEQ ID NO:
- 6;
- and
- vi) a probe for detecting adenovirus consisting of the polynucleotide set forth in SEQ ID NO:
- 7.
Dependencies are inferred from the claim text.