Back to results
US 9,958,516 B2Granted
Biological detector and method
AssigneesABQMR, Inc., Sandia Corporation, Stc.Unm
InventorsLaurel Sillerud, Todd M. Alam, Andrew F. McDowell
Life of this patent
Estimating the term…
Abstract
A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid.
Claims10
A method for detecting a target analyte in a sample, the method comprising:
- introducing magnetic particles comprising target-specific moieties to a sample comprising a plurality of target analytes under conditions such that at least one cluster of magnetic particles and target analytes is formed;
- and
- using a nuclear magnetic resonance (NMR) device in order to measure a signal due to a change in relaxation rate, wherein the relaxation rate changes in the presence of the at least one cluster, thereby detecting the target analyte in the sample.
Dependencies are inferred from the claim text.