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US 9,958,441 B2Granted
Nanostructured devices for detecting and analyzing biomolecules
AssigneeGeneral Electric Company
InventorsAn-Ping Zhang, Anthony John Murray, Rui Chen
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Abstract
A biosensing FET device, comprising a plurality of nanostructured SOI channels, that is adapted to operate in solutions having a high ionic strength and provides improves sensitivity and detection. Generally, the biosensing device comprises an underlying substrate layer, an insulator and a semiconductor layer and a plurality of channels in the semiconductor layer comprising a plurality of whole or partially formed nanopores in the channels.
Claims12
A method of making a biosensing device comprising:
- (a) providing an underlying substrate layer;
- (b) disposing an insulator on the substrate;
- (c) disposing a semiconductor, having an exposed surface with one or more channels, on the insulator layer;
- (d) forming one or more nanopores in one or more of the channels;
- and
- (e) functionalizing the one or more nanopores with a biomolecule binder.
3 more elements
Dependencies are inferred from the claim text.