Method for regulating acid resistance of microbes
AssigneeKabushiki Kaisha Yakult Honsha
InventorsHoshitaka Matsumoto, Mika Miura, Mayumi Kiwaki, Tohru Iino
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Abstract
Provided are a method for regulating acid resistance of a microorganism by suppressing the expression of the fadD gene therein and a screening method for a microorganism having acid resistance by using the expression level of the fadD gene as an index. A method for regulating acid resistance of a microorganism, including suppressing the expression of fadD gene present in the microorganism.
Claims20
A method for modifying acid resistance of a microorganism, the method comprising:
- modifying expression of fadD gene present in the microorganism;
- and
- selecting a microorganism having modified acid resistance.
A method for regulating acid resistance of a microorganism, the method comprising:
- controlling expression of fadD gene present in the microorganism by modifying a transcription promoter of the fadD gene.
A screening method for a microorganism having acid resistance, the method comprising:
- detecting the presence of fadD gene, absence of fadD gene, presence of an expression product of fadD gene, absence of an expression product of fadD gene, or a combination thereof, or measuring expression level of fadD gene, expression level of an expression product of fadD gene, or a combination thereof, in a microorganism;
- selecting a microorganism exhibiting inhibited or suppressed transcription of the fadD gene;
- and
- culturing the selected microorganism in a culture medium.
Dependencies are inferred from the claim text.