Weight loss by inhibition of gastrokine
AssigneeLumen Bio LLC
InventorDavid Lawrence Boone
Life of this patent
Estimating the term…
Abstract
Gastrokine-1 (Gkn-1) is a stomach protein that protects the gastrointestinal (GI) tract and has properties to manipulate smooth muscle contraction, prevent NSAID-induced ulceration of the gastrointestinal tract of a mammal, inhibit growth and survival of cancer cells and induce weight loss in a mammal. Previously this protein was designated AMP-18.
Claims13
A method to promote weight loss in a mammal, the method comprising administering an agent to the mammal, wherein the agent inhibits the action of Gkn-1 in the mammal, wherein the agent is an antibody or immunoglobulin, wherein the mammal does not have colitis, and wherein the agent inhibits the action of Gkn-1 in the mammal by binding to and neutralizing Gkn-1 in the mammal, thereby promoting weight loss in the mammal.
An agent that inhibits the action of Gkn-1, wherein the agent, when administered to a mammal, promotes weight loss, wherein the agent is an antibody or immunoglobulin, wherein the mammal does not have colitis, and wherein the agent inhibits the action of Gkn-1 in the mammal by binding to and neutralizing the Gkn-1 in the mammal.
A method for promoting weight loss in a mammal, wherein the mammal consumes an egg or egg meal from one or more eggs of one or more chickens inoculated with Gkn-1, wherein an anti-Gkn-1 antibody or immunoglobulin is deposited in the egg as a result of inoculating the one or more chickens with Gkn-1, wherein the mammal does not have colitis, and wherein the anti-Gkn-1 antibody or immunoglobulin binds to and neutralizes the Gkn-1 inside the mammal, thereby promoting weight loss in the mammal.
Dependencies are inferred from the claim text.