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US 9,957,287 B2Granted
Methods and compositions to treat type-1 and type-2 diabetes
AssigneeCornell University
InventorsLing Qi, Shengyi Sun, Yewei Ji
Life of this patent
Estimating the term…
Abstract
The present disclosure is directed to novel methods of treating type-1 or type-2 diabetes by inactivating TLR2 and TLR4 genes together in cells capable of producing insulin and/or regenerating β cells, and providing the cells to a subject in need thereof.
Claims21
A method for the treatment of diabetes in a subject, comprising providing insulin-producing cells to the subject, wherein the TLR2 and TLR4 genes in said cells have been inactivated.
Dependencies are inferred from the claim text.