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US 9,957,257 B2Granted
Amide compounds as 5-HT4 receptor agonists
AssigneeSuven Life Sciences Limited
InventorsRamakrishna Nirogi, Anil Karbhari Shinde, Abdul Rasheed Mohammed, Sangram Keshari Saraf, Narsimha Bogaraju, Ramkumar Subramanian, Pradeep Jayarajan, Gopinadh Bhyrapuneni, Venkateswarlu Jasti
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Abstract
The present invention relates to compounds of formula (I), including their stereoisomers and pharmaceutically acceptable salts. This invention also relates to methods of making such compounds and pharmaceutical compositions comprising such compounds. The compounds of this invention are useful in the treatment of various disorders that are related to 5-hydroxytryptamine 4 (5-HT4) receptor.
Claims9
A compound of the general formula (I),
- or a stereoisomer, a pharmaceutically acceptable salt thereof,
- wherein,
- X is halogen or hydrogen;
- “” is point of attachment;
- “” is bond or no bond;
- R1 is hydrogen, fluorine or hydroxyl;
- R2 is hydrogen or fluorine;
- provided that R2 is fluorine when “” is no bond;
- and
- “n” is 1 or 2.
7 more elements
Dependencies are inferred from the claim text.