US 9,956,554 B2 · Centrifugation method with a reversed syringe position

Abstract

According to one exemplary embodiment of the present invention, a method of centrifuging a mixture using a syringe which has a nozzle at one end, comprises the steps of taking the mixture in the syringe, first centrifuging the mixture in the syringe, discharging one part of the mixture which is adjacent to the nozzle after the first centrifuging, second centrifuging the mixture in the syringe after reversing the syringe, and discharging another part of the mixture which is adjacent to the nozzle after the second centrifuging.

Drawings

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Drawings

Claims5

Dependent claims

A method of centrifuging a mixture including red blood cells using a syringe which has only a single chamber and a nozzle at one end thereof, the method comprising the steps of:

(a) taking the mixture including red blood cells in the syringe directly from a patient;
(b) first centrifuging the mixture in the single chamber of the syringe at a first rotational speed to separate the mixture into at least a first part, a second part, and a third part, the nozzle of the syringe being directed opposite to a rotating center of a centrifuging device, wherein no parts of the syringe move relative to each other during the first centrifuging;
(c) discharging the first part of the mixture which is adjacent to the nozzle after the first centrifuging while leaving the second part and the third part in the single chamber;
(d) second centrifuging the mixture second part and the third part remaining in the single chamber of the syringe at a second rotational speed after step (c) after reversing the syringe, the second centrifuging to reverse the positioning of the second part and the third part within the single chamber, the nozzle of the syringe being directed to the rotating center, wherein no parts of the syringe move relative to each other during the second centrifuging;
and
(e) discharging the third part of the mixture which is adjacent to the nozzle after the second centrifuging such that only the second part remains in the single chamber of the syringe;
wherein the second rotational speed is higher than the first rotational speed.

4 more elements

Dependencies are inferred from the claim text.

Description17,487 words

Summary3,326 words

#The present invention relates to a method and a device for centrifuging, more particularly, relates to a method and a device for centrifuging a mixture quickly and simply.

#In general, blood is composed of blood cells and blood plasma. The blood cells are classes as red blood cell, white blood cell and blood platelet. The blood plasma is mainly composed of water and includes some blood coagulation element and ions.

#As mentioned the above, blood is a mixture which includes various elements. In these days, blood extracting technologies for lots of medical uses are widely spread, and especially blood centrifugations are generally used.

Brief description of the drawings44 figures

#FIG. 1 is a block diagram illustrating a centrifuging method according to a first embodiment of the present invention,

#FIGS. 2 to 4 are sectional views illustrating processes of a first centrifuging and discharging to remove one part of a mixture according to the first embodiment of the present invention,

#FIGS. 5 to 7 are sectional views illustrating processes of a second centrifuging and discharging to remove another part of the remained mixture according to the first embodiment of the present invention,

Detailed description13,172 words

#Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the like elements throughout. The embodiments are described below in order to explain the present invention by referring to the figures.

#FIG. 1 is a block diagram illustrating a centrifuging method according to a first embodiment of the present invention, FIGS. 2 to 4 are sectional views illustrating processes of a first centrifuging and discharging to remove one part of a mixture according to the first embodiment of the present invention, FIGS. 5 to 7 are sectional views illustrating processes of a second centrifuging and discharging to remove another part of the remained mixture according to the first embodiment of the present invention, and FIG. 8 is a sectional view illustrating a practical usage of target element extracted after the second centrifuging according to the first embodiment of the present invention.

#Referring to FIG. 1, a centrifuging method according to the first embodiment of the present invention may be performed by using a syringe 1100 which has a nozzle 1112 at its one end. The centrifuging method comprises taking the mixture in the syringe 1100 (S1010), first centrifuging the mixture in the syringe 1100 (S1020), discharging one part of the mixture which is adjacent to the nozzle 1112 after the first centrifuging (S1030), second centrifuging the mixture in the syringe 1100 after reversing the syringe 1100 (S1040), and discharging another part of the mixture which is adjacent to the nozzle 1112 after the second centrifuging (S1050).

Facts

Application

13/878,995Filed 12 Oct 2011

Priority

KR 10-2010-009912312 Oct 2010

Published

US 2014/0148325 A129 May 2014

Granted

1 May 2018

Term ends

27 Mar 2033

Estimated · how

20 years from earliest known nonprovisional domestic filing plus recorded patent term adjustment, including 532 days of adjustment. Maintenance-fee lapses, terminal disclaimers and statutory extensions have not been checked. The continuity chain may be incomplete; this is not an enforceability determination.

Classification10 codes

A61M 1/3693
Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood…
B01L 3/5021
With fluid transport, e.g. in multi-compartment structures: test tubes specially adapted for centrifugation purposes
B04B 5/0414
For liquids contained in receptacles: comprising test tubes
G01N 33/491
Blood: by separating the blood components

Timeline

12 Oct 2010Priority claimedKR 10-2010-0099123
12 Oct 2011Application filedUS 13/878,995
3 Jun 2013Assigned to Snu R&Db Foundationassignment of assignor's interest
29 May 2014PublishedUS 2014/0148325 A1
1 May 2018GrantedUS 9,956,554 B2
12 Oct 2026TodayWithin its term
27 Mar 2033Term endsEstimated, includes 532 days of adjustment

Centrifugation method with a reversed syringe position

Life of this patent

Centrifugation method with a reversed syringe position

Life of this patent

Life of this patent

Abstract

Drawings

Drawings

Claims5

Description17,487 words

Drawings

Classification10 codes

Life of this patent

Description17,487 words