Minimally invasive treatment of vertebra (MITV) using a calcium phosphate combination bone cement
AssigneeLife Science Enterprises, Inc.
InventorsAliassghar N. Tofighi, Aron D. Rosenberg, Tak Lung Chang, Michael Strunk
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Abstract
Featured are a biocompatible, injectable, self-setting, cohesive, bone-bonding and remodeling calcium phosphate composite material and its use in methods of repairing defective bone, e.g., in vertebroplasty augmentation and kyphoplasty.
Claims19
A flowable bone cement comprising a nanocrystalline apatitic calcium phosphate material, a radio-opaque agent, a pharmaceutically acceptable fluid, and carboxymethyl cellulose in an amount of less than 10% by weight, wherein said nanocrystalline apatitic calcium phosphate material comprises crystals having a domain size within the range of 30-80 nm, said flowable bone cement hardens in less than 1 hour at 37° C. and, after hardening, has a compressive strength of 1 MPa or greater and is resorbable in vivo.
Dependencies are inferred from the claim text.