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US 9,956,285 B2Granted
Anti-viral compounds
AssigneeKineta, Inc.
InventorsShawn P. Iadonato, Kristin M. Bedard, Myra Wang Imanaka, Kerry W. Fowler
Life of this patent
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Abstract
Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.
Claims6
A method of treating a viral infection in a vertebrate, comprising administering to a vertebrate an effective amount of a compound represented by the formula
- or a pharmaceutically acceptable salt thereof, wherein said viral infection is caused by a virus selected from the group consisting of influenza virus, Dengue virus, Hepatitis B virus, and respiratory syncytial virus.
A method of modulating the innate immune response in a eukaryotic cell, comprising administering to a eukaryotic cell a compound represented by the formula
- or a pharmaceutically acceptable salt thereof, wherein said modulating is activation of interferon regulatory factor-3 (IRF-3).
Dependencies are inferred from the claim text.