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US 9,956,275 B2Granted
Methods of inhibiting platelet aggregation and preventing thrombosis using antibodies that bind (Na++K+)-ATPase beta subunit
OwnerKai Yuan Xuinventor
Life of this patent
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Abstract
Methods of inhibiting platelet activation and aggregation using peptide vaccine or antibodies that have binding specificity for the β subunit of the (Na++K+)-ATPase are provided, along with methods for inhibiting or preventing thrombosis in a subject using such peptide vaccine or antibodies.
Claims2
A method of inhibiting thrombosis in a subject comprising administering a pharmaceutically effective synthetic peptide vaccine to a subject in need thereof, wherein said peptide vaccine comprises a synthetic peptide selected from SEQ ID NOS:
- 1-6 and a pharmaceutically acceptable carrier, wherein said peptide vaccine stimulates the host immune system to generate endogenous antibodies that specifically bind to the β1 subunit of the (Na++K+)-ATPase.
Dependencies are inferred from the claim text.