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US 9,956,253 B2Granted
Placental tissue grafts
AssigneeMiMedx Group, Inc.
InventorJohn Daniel
Life of this patent
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AssigneeMiMedx Group, Inc.
InventorJohn Daniel
Estimating the term…
A method for preparing placenta membrane tissue grafts for medical use, includes obtaining a placenta from a subject, cleaning the placenta, separating the chorion tissue from the amniotic membrane, mounting a selected layer of either the chorion tissue or the amniotic membrane onto a drying fixture, dehydrating the selected layer on the drying fixture, and cutting the selected layer into a plurality of tissue grafts. Preferably, the drying fixture includes grooves or raised edges that define the outer contours of each desired tissue graft, after they are cut, and further includes raised or indented logos that emboss the middle area of the tissue grafts during dehydration and that enables an end user to distinguish the top from the bottom side of the graft. The grafts are comprised of single layers of amnion or chorion, multiple layers of amnion or chorion, or multiple layers of a combination of amnion and chorion.
A dehydrated, laminated bilayer tissue graft consisting of
A dehydrated, laminated bilayer tissue graft, wherein the tissue graft consists of an amnion layer and a chorion layer, wherein the amnion layer consists of an epithelial cellular layer, a basement membrane, a compact layer, and a fibroblast cellular layer, and wherein each of the amnion and chorion layers:
A dehydrated, laminated placental tissue graft which is a laminate consisting of two washed layers,
Dependencies are inferred from the claim text.