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US 9,956,215 B1Granted
Methods of treating cancer with farnesyltransferase inhibitors
AssigneeKura Oncology, Inc.
InventorsAntonio Gualberto, Catherine Rose Scholz
Life of this patent
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Abstract
The present invention relates to the field of cancer therapy. Specifically, provided are methods of treating cancer, for example, peripheral T-cell lymphoma (“PTCL”), with a farnesyltransferase inhibitor (FTI) that include determining whether the subject is likely to be responsive to the FTI treatment based on gene expression characteristics.
Claims30
A method of treating a CXCL12-expressing cancer in a subject, comprising administering a therapeutically effective amount of tipifarnib to the subject, wherein the cancer is peripheral T-cell lymphoma (PTCL) or acute myeloid leukemia (AML).
Dependencies are inferred from the claim text.