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US 9,956,212 B2Granted
Quinoline carboxamides for use in the treatment of multiple myeloma
AssigneeActive Biotech AB
InventorsDavid Liberg, Anders Olsson, Dmitry Gabrilovich, Yuliya Nefedova
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Abstract
A compound of formula (I), or a pharmaceutically acceptable salt thereof, for use in the treatment of multiple myeloma.
Claims20
A method of treatment of multiple myeloma by administration to a mammal in need thereof of a compound of formula (I)
- or a pharmaceutically acceptable salt thereof,
- wherein
- R1 is selected from hydrogen, methyl, ethyl, n-propyl, iso-propyl, methoxy, ethoxy, fluoro, chloro, bromo, trifluoromethyl, and trifluoromethoxy;
- R2 is C1-C4 alkyl;
- R3 is selected from methyl, methoxy, fluoro, chloro, bromo, trifluoromethyl, and trifluoromethoxy;
- and
- R4 is selected from hydrogen, fluoro and chloro, with the proviso that R4 is selected from fluoro and chloro only when R3 is selected from fluoro and chloro.
4 more elements
Dependencies are inferred from the claim text.