Skin-protection composition containing dendrobium-based ingredients

A compound comprising formula (4):

• wherein
• R2, R4, and R8 are each independently selected from —OR11, —OCH2R12, —OC(O)R11, —OCH2C(O)OR12 and —OC(O)CH2R12;
• R1, R3, R5, R6, R7, R9 and R10 are each independently selected from hydrogen, halogen, trifluoromethyl, —OR12 and —OC(O)R12;
• or R2 and R3, or R7 and R8 may be taken together with the carbon atoms to which they are attached to form a cyclic group;
• R11 is independently selected from —(CH2)-hydrocarbyl, C2-10 alkyl, alkenyl, carbocyclyl, aryl and heteroaryl, wherein each of these groups is optionally substituted with 1, 2, 3, 4 or 5 R13;
• R12 is independently selected from hydrocarbyl and heterocyclyl, either of which is optionally substituted with 1, 2, 3, 4 or 5 R13;
• R13 is independently selected from halogen, trifluoromethyl, cyano, nitro, oxo, —OR14, —C(O)R15, —C(O)N(R14)R15, —C(O)OR14, —OC(O)R15, —S(O)2R14, —S(O)2N(R14)R15, —N(R14)R15;
• R14 and R15 are each independently hydrogen or selected from hydrocarbyl and heterocyclyl, either of which is optionally substituted with 1, 2, 3, 4 or 5 substituents independently selected from halogen, cyano, amino, hydroxy, C1-6 alkyl and C1-6 alkoxy
• or a pharmaceutically acceptable salt, prodrug, derivative or chemical variant thereof.