Radioisotope concentrator
AssigneeCyclopharm Limited
InventorsVan So Le, Nabil Marcos, James McBrayer
Life of this patent
Estimating the term…
Abstract
A system using a radioisotope concentrator device comprising a body having at least one injection port and at least one valve being configurable between a first open configuration for allowing fluid communication between the at least one injection port and the concentrator column and a second open configuration to prevent fluid communication between the at least one injection port and the concentrator column in use, the system further comprising an injection device comprising an eluent for eluting through the concentrator column via the at least one injection port when the at least one valve of the radioisotope concentrator device is in a selected open configuration in use.
Claims18
A radioisotope concentrator device for use with a radioisotope source, the radioisotope concentrator device comprising:
- a body having an internal volume in the form of a multiple use sterile disposable cartridge including a concentrator column, a competitive ion selective column, an injection device comprising at least one injection port, one multiple way valve, one entry port at a lower location, and one exit port at an upper location, all being in fluid communication;
- the concentrator column disposed within the internal volume being adapted for selectively capturing at least one radioisotope from a radioisotope solution obtained from a radioisotope source in use, and the body having shielding means for shielding at least the concentrator column in use;
- the competitive ion selective column disposed within the internal volume being adapted for removing at least one competitive ion from the radioisotope solution obtained from the radioisotope source in use;
- the at least one injection port adapted to receive an injection device, and the at least one injection port being operably connected to the concentrator column;
- the one multiple way valve being configurable between a first open configuration for allowing fluid communication between the competitive ion selective column and the concentrator column in use and a second open configuration for allowing fluid communication between the at least one injection port and the concentrator column to elute the at least one radioisotope from the concentrator column with an eluent;
- and
- wherein the at least one exit port, being in fluid communication with the internal volume and the at least one exit port, is able to connect to an evacuated vial in use to effect, by the vacuum provided by the waste vial, the fluid communication in the first open configuration or in the second open configuration and whereby the vacuum within the evacuated vial imparts a negative pressure on the system causing the solution of the radioisotope with the eluent to be drawn up through the competitive ion selective column and the concentrator column into the vial.
Dependencies are inferred from the claim text.