Combination for treating an inflammatory disorder

A method for treating an inflammatory condition or disease selected from:

• rheumatoid arthritis (RA), juvenile rheumatoid arthritis, osteoarthritis (OA), gout, spondlyarthritis (SpA), psoriasis, psoriatic arthritis, ankylosing spondylitis, inflammatory bowel disease including Crohn's disease or ulcerative colitis, hepatitis, sepsis, alcoholic liver disease, and non-alcoholic steatosis, pain, ischemic disorder, glaucoma, asthma, arthritis, cancer, neurodegenerative disorders, chronic disorders, acute inflammation, blood clotting disorders, heart failure, and disorder of platelet function, the method comprising administering to a person in need thereof a combination of:
• (a) a source of a CD39 comprising a nucleic acid molecule encoding the CD39 and
• (b) a source of a CD73 comprising a nucleic acid molecule encoding the CD73,
• wherein the nucleic acid molecules encoding the CD39 and the CD73 are present in a nucleic acid construct comprising a viral expression construct selected from a retrovirus vector, an adenovirus vector, an adeno-associated virus vector, a herpesvirus vector, a polyoma virus vector or a vaccinia virus vector.