Back to results
US 9,939,449 B2Granted
Diagnostic and therapeutic methods and products related to anxiety disorders
AssigneeUniversity of Vermont and State Agricultural College
InventorsVictor May, Kerry J. Ressler, Sayamwong E. Hammack, Donna Toufexis, Karen M. Braas
Life of this patent
Estimating the term…
Abstract
The present disclosure provides methods for diagnosing and treating anxiety disorders in female subjects. Diagnosis and treatment of such anxiety disorders are based, in part, on an analysis of pituitary adenylate cyclase-activating polypeptide (PACAP) expression levels in tissue collected from female subjects.
Claims8
A method for diagnosing and treating post traumatic stress disorder (PTSD) in a female human, comprising:
- a) analyzing pituitary adenylate cyclase-activating polypeptide (PACAP) expression levels in a tissue sample collected from a female human;
- b) diagnosing PTSD in the female human having elevated tissue PACAP expression levels as compared to a control tissue sample obtained from a subject who does not have PTSD;
- and
- c) administering to the female human diagnosed in (b) a therapeutically effective amount of an antibody that binds specifically to an epitope at the carboxy-terminal end of PACAP.
1 more element
Dependencies are inferred from the claim text.