Uses of monoclonal antibody 8H9
AssigneeSloan-Kettering Institute for Cancer Research
InventorNai-Kong V. Cheung
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AssigneeSloan-Kettering Institute for Cancer Research
InventorNai-Kong V. Cheung
Estimating the term…
This invention provides a composition comprising an effective amount of monoclonal antibody 8H9 or a derivative thereof and a suitable carrier. This invention provides a pharmaceutical composition comprising an effective amount of monoclonal antibody 8H9 or a derivative thereof and a pharmaceutically acceptable carrier. This invention also provides an antibody other than the monoclonal antibody 8H9 comprising the complementary determining regions of monoclonal antibody 8H9 or a derivative thereof, capable of binding to the same antigen as the monoclonal antibody 8H9. This invention provides a substance capable of competitively inhibiting the binding of monoclonal antibody 8H9. This invention also provides an isolated scFv of monoclonal antibody 8H9 or a derivative thereof. This invention also provides the 8H9 antigen. This invention also provides a method of inhibiting the growth of tumor cells comprising contacting said tumor cells with an appropriate amount of monoclonal antibody 8H9 or a derivative thereof.
A method of inhibiting the growth of tumor cells that express 8H9 antigen, comprising the step of contacting said tumor cells with an isolated antibody, said antibody comprises Complementary Determining Regions having the sequences of SEQ ID NOs.29-34.
A method of inhibiting the growth of tumor cells that express 8H9 antigen in a subject, comprising the step of administering to said subject an isolated antibody, said antibody comprises Complementary Determining Regions having the sequences of SEQ ID NOs.29-34.
Dependencies are inferred from the claim text.