Methods and apparatus for gas stream mass transfer with a liquid

A system for performing a gas-liquid mass transfer comprising:

• a) a container bounding a compartment and having a top wall, a bottom wall, and an encircling sidewall extending therebetween, the container comprising a flexible bag having a sterile compartment configured to hold a fluid;
• b) a plurality of vertically spaced apart openings being formed on the sidewall of the container so as to communicate with the compartment;
• c) a gas source coupled to each of the vertically spaced apart openings;
• d) a liquid disposed within the compartment and having a top surface;
• and
• e) a gas blowing through one of the plurality of vertically spaced apart openings, the one of the plurality of vertically spaced apart openings being disposed above the top surface of the liquid, so that the gas passes over at least a portion of the top surface of the liquid.

A system for performing a gas-liquid mass transfer comprising:

• a) a container bounding a compartment and having a top wall, a bottom wall, and an encircling sidewall extending therebetween, the container comprising a flexible bag;
• b) a first opening formed on the container so as to communicate with the compartment;
• c) a liquid disposed within the compartment and having a top surface disposed below the first opening;
• d) a gas blowing through the first opening so that the gas passes over at least a portion of the top surface of the liquid;
• and
• e) means for mixing the liquid within the compartment.

A system for performing a gas-liquid mass transfer comprising:

• a) a container bounding a compartment and having a top wall, a bottom wall, and an encircling sidewall extending therebetween;
• b) a first opening formed on the container so as to communicate with the compartment;
• c) a liquid disposed within the compartment and having a top surface disposed below the first opening;
• d) a gas blowing through the first opening so that the gas passes over at least a portion of the top surface of the liquid, the gas flowing over the at least a portion of top surface of the liquid at a velocity of at least 40 m/sec;
• and
• e) means for mixing the liquid within the compartment.

A system for performing a gas-liquid mass transfer comprising:

• a) a container bounding a compartment and having a top wall, a bottom wall, and an encircling sidewall extending therebetween;
• b) a first opening formed on the container so as to communicate with the compartment;
• c) a liquid disposed within the compartment and having a top surface disposed below the first opening;
• d) a gas sparger coupled with the container and communicating with the liquid;
• e) a gas blowing through the first opening so that the gas passes over at least a portion of the top surface of the liquid;
• and
• f) means for mixing the liquid within the compartment.